Sialic acid review accepted

9th October, 2011

Good news, the latest collaborative effort with the Sharma Group has been accepted for publication as a review in the journal Molecular and Oral Microbiology. This represents a deal of work over this summer and is the first review of siallobiology of periodontal pathogens.  It summarises current knowledge and points out area for future investigation while also hinting at some areas we have an inkling about from recent work.




The role of sialic acid in terms of periodontitis is clearly complex but is emerging as having a significant role as can be seen in the accompanying diagram and several publications in this area in recent years.  This diagram illustrates the myriad of possible interactions between host and bacteria in terms of sialic acid and sialidase enzymes (From Stafford et al., 2011).